| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Ahmed El Shenawi | Bodyguard | Colt Python | "Blind Run" (S2E9) |
| Anthony Bailey | Phipps | Colt Python | "Man Without a Past" (S2E4) |
| Chai Lee | Esther | Walther PPK | "Take Away" (S4E6) |
| David Suchet | Krivas | SIG P210 | "Where the Jungle Ends" (S01E06) |
| Gordon Jackson | George Cowley | Smith & Wesson Model 36 | Seasons 1-5 |
| Ian McDiarmid | Mickey Hamilton | L1A1 | "Madness of Mickey Hamilton" (S03E05) |
| John Castle | Tommy | Ithaca 37 "Stakeout" | - |
| John Castle | Tommy | FN FAL | - |
| Martin Shaw | Doyle | Inglis Hi-Power | primary gun seasons 1-3 |
| Martin Shaw | Doyle | Smith & Wesson Model 29 | - |
| Martin Shaw | Doyle | Walther P38 | primary gun, seasons 3-5 |
| Martin Shaw | Doyle | Armalite AR-10 | - |
| Martin Shaw | Doyle | Enfield XL64E5 | "Wild Justice" (S04E02) |
| Michael Byrne | Werner | SIG P210 | Fugitive |
| Vickery Turner | Karen | Smith & Wesson Model 40 | "Fugitive" (S4E3) |