| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Amy Morton | Sgt. Trudy Platt | Smith & Wesson Model 60 | - |
| Bokeem Woodbine | Derek Keyes | Colt Officer's ACP | Novak-style sights, flared magwell, slanted slide serrations, skeletonized hammer and trigger, and ambidextrous safety |
| Brian Geraghty | Officer Sean Roman | Glock 17 | - |
| Danny Pino | Detective Nick Amaro | Glock 19 | "They'll Have to Go Through Me" (S2E07) |
| Elias Koteas | Detective Alvin Olinsky | Glock 17 | - |
| Elias Koteas | Detective Alvin Olinsky | M4A1 | - |
| Elias Koteas | Detective Alvin Olinsky | Smith & Wesson Model 36 | - |
| Jason Beghe | Sgt. Henry "Hank" Voight | SIG-Sauer P229R | - |
| Jason Beghe | Sgt. Henry "Hank" Voight | SIG-Sauer P226R | - |
| Jason Beghe | Sgt. Henry "Hank" Voight | Glock 17 | - |
| Jason Beghe | Sgt. Henry "Hank" Voight | M4A1 | - |
| Jesse Lee Soffer | Detective Jay Halstead | Glock 17 | - |
| Jesse Lee Soffer | Detective Jay Halstead | M4A1 | - |
| Jon Seda | Det. Antonio Dawson | Glock 17 | - |
| Jon Seda | Det. Antonio Dawson | M4A1 | - |
| LaRoyce Hawkins | Officer Kevin Atwater | Glock 17 | - |
| LaRoyce Hawkins | Officer Kevin Atwater | Springfield Champion Operator Lightweight | - |
| LaRoyce Hawkins | Officer Kevin Atwater | M4A1 | - |
| Marina Squerciati | Officer Kim Burgess | Glock 17 | - |
| Marina Squerciati | Officer Kim Burgess | Taser X26 | - |
| Patrick John Flueger | Officer Adam Ruzek | Glock 17 | - |
| Patrick John Flueger | Officer Adam Ruzek | Springfield TRP Operator | - |
| Sophia Bush | Det. Erin Lindsay | Glock 19 | - |
| Sophia Bush | Det. Erin Lindsay | Glock 17 | Gen 2, Continuity Error |
| Tracy Spiridakos | Det. Hailey Upton | Glock 17 | - |