| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Samuel L. Jackson | Nick Fury | Smith & Wesson M&P | - |
| Scarlett Johansson | Natasha Romanoff | Glock 26 | dual wielded |
| Scarlett Johansson | Natasha Romanoff | Glock 19 | - |
| Scarlett Johansson | Natasha Romanoff | M203A1 Grenade Launcher | fitted underneath M4A1 |
| Anthony Mackie | Sam Wilson | Steyr SPP | dual-wielded |
| Anthony Mackie | Sam Wilson / "Falcon" | M4A1 | - |
| Anthony Mackie | Sam Wilson / "Falcon" | MAC-10 | continuity error |
| Callan Mulvey | Jack Rollins | M4A1 | w/EOTech, suppressor |
| Callan Mulvey | Jack Rollins | Glock 19 | - |
| Chin Han | Councilman Yen | Glock 19 | - |
| Chris Evans | Steve Rogers | M1 Garand | - |
| Chris Evans | Steve Rogers/Captain America | M67 Hand Grenade | - |
| Cobie Smulders | Agent Maria Hill | Glock 19 | - |
| Cobie Smulders | Agent Maria Hill | M4A1 | - |
| Emily VanCamp | Sharon/Agent 13 | FNP-45 Tactical | - |
| Emily VanCamp | Sharon/Agent 13 | Glock 19 | - |
| Frank Grillo | STRIKE Agent Brock Rumlow | M4A1 | M4 upper on an AR-15 (SP1) lower receiver, EOTech holographic sight, vertical foregrip, tactical flashlight and Magpul PMag |
| Frank Grillo | STRIKE Agent Brock Rumlow | Steyr AUG A3 | DCL 110 sight used as fictional optic, and suppressor |
| Frank Grillo | STRIKE Agent Brock Rumlow | Glock 19 | - |
| Frank Grillo | STRIKE Agent Brock Rumlow | SIG-Sauer P226 | customized |
| Frank Grillo | STRIKE Agent Brock Rumlow | FN FNX-45 Tactical | - |
| Jenny Agutter | Council member Hawley | Glock 19 | - |
| Robert Redford | Alexander Pierce | SIG-Sauer P220 Combat | nickel plated, Non gun |
| Robert Redford | Alexander Pierce | Glock 19 | - |
| Salvator Xuereb | French Pirate #1 | Heckler & Koch G36C | - |
| Sebastian Stan | The Winter Soldier | M4A1 | with M203A1 Grenade Launcher |
| Sebastian Stan | The Winter Soldier | SIG-Sauer P220 Combat | nickel |
| Sebastian Stan | The Winter Soldier | Milkor MGL | - |
| Sebastian Stan | The Winter Soldier | COP 357 Derringer | - |
| Sebastian Stan | The Winter Soldier | Sa vz. 61 Skorpion | - |
| Sebastian Stan | The Winter Soldier | Intratec TEC-38 | - |
| Stan Lee | Smithsonian Guard | Glock 17 | - |