| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Samuel L. Jackson | Major Marquis "The Bounty Hunter" Warren | Single Action Army | dual-wielded |
| Kurt Russell | John Ruth, the "Hangman" | Remington 1858 New Army "Cattleman's Carbine" | - |
| Kurt Russell | John Ruth, the "Hangman" | Single Action Army | - |
| Channing Tatum | Jody Domingre | Colt 1878 Double Action | - |
| Demián Bichir | Bob | Single Action Army | - |
| Michael Madsen | Joe Gage | Colt 1851 Navy | Richards-Mason conversion, ivory grips |
| Michael Madsen | Joe Gage | Coach Gun | - |
| Michael Madsen | Joe Gage | Colt Walker | Ivory grips |
| Tim Roth | Oswaldo Mobray | Richards Cartridge Conversion | Cartridge conversion |
| Tim Roth | Oswaldo Mobray | British Bulldog | - |
| Walton Goggins | Chris Mannix | Single Action Army | - |
| Walton Goggins | Chris Mannix | Remington 1858 New Army "Cattleman's Carbine" | - |