| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Angel Aviles | Zamira | Beretta 93R | - |
| Antonio Banderas | El Mariachi | Ruger KP90 | akimbo |
| Antonio Banderas | El Mariachi | Desert Eagle Mark XIX | - |
| Antonio Banderas | El Mariachi | Wildey Magnum | scoped |
| Antonio Banderas | El Mariachi | Rossi Overland | sawed off |
| Antonio Banderas | El Mariachi | Sentinel Arms Stryker 12 | - |
| Antonio Banderas | El Mariachi | MAC-10 | - |
| Antonio Banderas | El Mariachi | M26 Hand Grenade | - |
| Carlos Gallardo | Campa | MAC-10 | hidden in guitar case |
| Carlos Gómez | Right Hand | Desert Eagle Mark XIX | - |
| Cheech Marin | The Tarasco Bartender | Smith & Wesson Model 19 | suppressed |
| Diego Sandoval | Empty Gun Man | Taurus PT99 | suppressed |
| Joaquim de Almeida | Bucho | M1911A1 | nickel |
| Joaquim de Almeida | Bucho | Desert Eagle Mark XIX | - |
| Joaquim de Almeida | Bucho | Beretta M93R | - |
| Mike Moroff | Shrug | Desert Eagle Mark XIX | .50 AE |
| Mike Moroff | Shrug | LAR Grizzly Win Mag | - |
| Peter Marquardt | Moco | 1911A1 Pistol | - |
| Tito Larriva | Tavo | Ruger KP90 | - |
| Tito Larriva | Tavo | Desert Eagle Mark XIX | black finish |