| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Anthony James | Ralph Henshaw | Smith & Wesson Model 20 | nickel |
| James Patterson | Mr. Purdy | Double Barreled Shotgun | - |
| Rod Steiger | Chief Bill Gillepsie | Smith & Wesson Model 20 | - |
| Sidney Poitier | Det. Virgil Tibbs | Smith & Wesson Model 20 | . |
| Warren Oates | Sgt. Sam Wood | Smith & Wesson Model 20 | With 4" barrel and factory wooden grips |