| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Avan Jogia | Leon Kennedy | M1911 | Nickel |
| Avan Jogia | Leon Kennedy | Saab Bofors Dynamics AT4 | Nickel |
| Chad Rook | Richard Aiken | Mossberg 590 | With heat shield |
| Donal Logue | Chief Irons | Smith & Wesson Model 29 | - |
| Hannah John-Kamen | Jill Valentine | Beretta 92FS | - |
| Hannah John-Kamen | Jill Valentine | Heckler & Koch MP5K-PDW | - |
| Kaya Scodelario | Claire Redfield | Beretta 92FS | - |
| Kaya Scodelario | Claire Redfield | Remington 870 | pistol grip |
| Robbie Amell | Chris Redfield | Beretta 92FS | - |
| Robbie Amell | Chris Redfield | Heckler & Koch MP5A3 | - |
| Tom Hopper | Albert Wesker | Beretta 92FS | - |
| Tom Hopper | Albert Wesker | Heckler & Koch MP5A3 | Surefire foregrip |