| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Benedict Cumberbatch | Sherlock Holmes | SIG-Sauer P226 | "The Great Game" (S1E03) (gas-powered Airsoft replica) |
| Martin Freeman | Dr. John Watson | SIG-Sauer P226 | "A Study In Pink" (S01E01), "The Great Game" (S01E03); Gas-powered Airsoft replica |
| Philip Davis | Jeff Hope (The Cabbie) | Tokyo Marui Hi-Capa 4.3 | "A Study in Pink" (S01E01), lighter |
| Rupert Graves | Inspector Lestrade | Glock 17 | Two-Tone |