| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Harrison Ford | Indiana Jones | Browning Hi-Power | - |
| Harrison Ford | Indiana Jones | Smith & Wesson M1917 Revolver | shortened barrel |
| Harrison Ford | Indiana Jones | Smith & Wesson Mk II Hand Ejector | shortened barrel |
| Harrison Ford | Indiana Jones | RPG-2 | - |
| Anthony Higgins | Maj. Gobler | Luger P08 | In holster |
| Billy Horrigan | Gunner | MG34 | Vehicle-mounted |
| Frank Marshall | Pilot | Walther P38 | - |
| Karen Allen | Marion Ravenwood | Mauser C96 | broomhandle |
| Karen Allen | Marion Ravenwood | MG15 machine gun | MG81Z machine gunmocked up as MG 15 |
| Paul Freeman | René Belloq | MP40 | anachronistic |
| Ronald Lacey | Maj. Arnold Toht | Walther P38 | - |
| Vic Tablian | Barranca | Remington 1875 | - |
| Wolf Kahler | Col. Herman Dietrich | Luger P08 | In holster |