| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Bill Henderson | Casper Lindley | Hawk MM1 grenade launcher | - |
| Christopher Lloyd | John Bigboote | MAC-10 | - |
| Ellen Barkin | Penny Priddy | Colt Model 1908 Vest Pocket | - |
| Jeff Goldblum | New Jersey | Colt Buntline Special | - |
| John Ashton | Highway Patrolman | Unknown revolver | In holster |
| Lewis Smith | Perfect Tommy | Heckler & Koch P7 | - |
| Pepe Serna | Reno Nevada | Walther PPK | - |
| Pepe Serna | Reno Nevada | Sterling SMG | - |
| Peter Weller | Buckaroo Banzai | Single Action Army | - |
| Peter Weller | Buckaroo Banzai | Colt Model 1903/1908 | - |