| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Billy Brown | Archer Petit | Smith & Wesson SW1911SC "E-Series" | - |
| Dylan McDermott | FBI Special Agent Duncan Carlisle | SIG-Sauer P229R | regular & two-tone |
| Dylan McDermott | FBI Special Agent Duncan Carlisle | Heckler & Koch USP Compact | - |
| Dylan McDermott | FBI Special Agent Duncan Carlisle | Smith & Wesson Model 65 | - |
| Rhys Coiro | Kramer | Heckler & Koch MP5A3 | "Pilot" (S1E01) |
| Tate Donovan | Brian Sanders | Smith & Wesson Model 65 | - |