| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Nicolas Cage | Castor Troy | Remington 700 | scope |
| Nicolas Cage | Castor Troy | Springfield Armory M1911-A1 | skeletonized hammers, beavertail grip safeties, ambidextrous slide stop safeties, target sites, moderately bevelled magazine wells, and V-10 ported slides/barrels |
| Nicolas Cage | Castor Troy | Benelli M2 Super 90 | - |
| Nicolas Cage | Sean Archer/Castor Troy | Beretta 92FS | - |
| Nicolas Cage | Sean Archer/Castor Troy | Stechkin APS | - |
| Nicolas Cage | Sean Archer/Castor Troy | IMI Mini Uzi | - |
| Alessandro Nivola | Pollux Troy | Sa. Vz.61 Skorpion | - |
| Chris Bauer | Ivan Dubov | Ruger AC556 | - |
| Dominique Swain | Jamie Archer | Beretta 92FS | - |
| Gina Gershon | Sasha Hassler | Springfield Armory M1911-A1 | skeletonized hammer, beavertail grip safety, ambidextrous slide stop safety, target sights, moderately bevelled magazine well, and V-10 ported slide/barrel |
| Gina Gershon | Sasha Hassler | Heckler & Koch MP5A3 | - |
| Gina Gershon | Sasha Hassler | Colt Model R0635 | - |
| Gina Gershon | Sasha Hassler | Smith & Wesson 3913 | - |
| James Denton | Buzz | SIG-Sauer P228 | - |
| James Denton | Buzz | Springfield Armory M1911A1 | - |
| James Denton | Buzz | Heckler & Koch MP5A2 | - |
| Joan Allen | Eve Archer | Smith & Wesson Model 36 | - |
| John Travolta | Sean Archer/Castor Troy | SIG-Sauer P226 | Two-Tone |
| John Travolta | Sean Archer | Smith & Wesson Model 686 | Snubnose |
| John Travolta | Sean Archer/Castor Troy | Beretta 92FS | - |
| John Travolta | Sean Archer/Castor Troy | Beretta 92FS Inox | - |
| John Travolta | Sean Archer/Castor Troy | Stechkin APS | - |
| John Travolta | Sean Archer/Castor Troy | Armscor BXP | - |
| John Travolta | Sean Archer/Castor Troy | Heckler & Koch MP5K | - |
| Kirk Baltz | Aldo | Smith & Wesson 3913 | - |
| Lauren Sinclair | Agent Winters | SIG-Sauer P230 | Stainless |
| Margaret Cho | Wanda | SIG-Sauer P228 | - |
| Matt Ross | Agent Loomis | Colt Sporter 1 Carbine | Fitted withM203 Grenade Launcher |
| Nick Cassavetes | Dietrich Hassler | Ithaca 37 | skeletonized stock and short barrel |
| Robert Wisdom | Special Agent Tito Biondi | Heckler & Koch MP5A2 | - |
| Tommy Flanagan | Leo | Armscor BXP | - |
| Tommy Flanagan | Leo | Ruger P89 | - |