| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Keanu Reeves | John Constantine | Holy Shotgun | - |
| Keanu Reeves | John Constantine | Dragon's Breath Flamethrower | - |
| Rachel Weisz | Angela Dodson | Smith & Wesson 3913 | - |
| Shia LaBeouf | Chaz Kramer | Mossberg 500 Cruiser | Extended Tube; 18" Barrel |