| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Cameron Diaz | Jenny Everdeane | Boot Pistol | - |
| Cameron Diaz | Jenny Everdeane | Joslyn Rifle | - |
| David Hemmings | Mr. Schermerhorns | Colt 1851 Navy | dual-wielded |
| Jim Broadbent | William "Boss" Tweed | Double Barreled Shotgun | - |
| John C. Reilly | Happy Jack Mulroney | Percussion Pocket Pistol | - |
| Leonardo DiCaprio | Amsterdam Vallon | Boot Pistol | - |
| Leonardo DiCaprio | Amsterdam Vallon | Colt 1849 Pocket | - |
| Leonardo DiCaprio | Amsterdam Vallon | Elgin Cutlass Pistol | - |
| Leonardo DiCaprio | Amsterdam Vallon | Roger & Spencer | - |