| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Chris Isaak | Memphis Police SWAT Team Leader | Ithaca 37 | - |
| Jodie Foster | Clarice Starling | Smith & Wesson Model 13 | 3" barrel, Pachmayr grip adapter |
| Scott Glenn | FBI Special Agent Jack Crawford | Remington 870 | short barrel |
| Ted Levine | Jame "Buffalo Bill" Gumb | Colt Python | stainless steel |