| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Chris Penn | "Nice Guy" Eddie | Smith & Wesson Model 66 | - |
| Harvey Keitel | Larry Dimmick/Mr. White | Smith & Wesson 639 | - |
| Harvey Keitel | Larry Dimmick/Mr. White | Smith & Wesson 659 | - |
| Lawrence Tierney | Joe Cabot | Colt Detective Special | - |
| Michael Madsen | Vic Vega/Mr. Blonde | Smith & Wesson 659 | - |
| Steve Buscemi | Mr. Pink | Smith & Wesson 659 | - |
| Steve Buscemi | Mr. Pink | Smith & Wesson 6906 | Continuity Error |
| Tim Roth | Freddy Newandyke/Mr. Orange | Beretta Jetfire | - |
| Tim Roth | Freddy Newandyke/Mr. Orange | Charter Arms Off Duty | Pachmayr grips |
| Tim Roth | Freddy Newandyke/Mr. Orange | Smith & Wesson 659 | Round trigger guard |