| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Matt Damon | Jason Bourne | SIG-Sauer P226R | - |
| Matt Damon | Jason Bourne | SIG-Sauer P225 | archival footage fromThe Bourne Identity |
| Matt Damon | Jason Bourne | Double Barreled Shotgun | archival footage fromThe Bourne Identity |
| Matt Damon | Jason Bourne | Glock 17 | archival footage fromThe Bourne Ultimatum |
| Matt Damon | Jason Bourne | Heckler & Koch USP | - |
| Matt Damon | Jason Bourne | Brügger & Thomet GL-06 | - |
| Matt Damon | Jason Bourne | Remington 870 | deleted scene |
| Alicia Vikander | Heather Lee | SIG-Sauer P226R | - |
| Julia Stiles | Nicky Parsons | Walther PPK | - |
| Tommy Lee Jones | Director Dewey | SIG-Sauer P228 | - |
| Vincent Cassel | The Asset | FN SCAR-L CQC | w/ scope & suppressor |
| Vincent Cassel | The Asset | SIG-Sauer SIG556 SWAT | w/ scope & suppressor |
| Vincent Cassel | The Asset | M4A1 | - |
| Vincent Cassel | The Asset | SIG-Sauer P228 | suppressed |
| Vincent Cassel | The Asset | Walther PPK | suppressed |