| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Christopher Lloyd | Emmett "Doc" Brown | Single Action Army | - |
| Christopher Lloyd | Emmett "Doc" Brown | Winchester Model 1866 "Yellow Boy" | large lever loop and custom scope |
| Donovan Scott | Deputy | Winchester Model 1873 | - |
| Dub Taylor | An old-timer | Single Action Army | - |
| James Tolkan | Marshal James Strickland | 12 Gauge Double Barreled Shotgun | - |
| Michael J. Fox | Seamus McFly | 12 Gauge Double Barreled Shotgun | - |
| Michael J. Fox | Marty McFly/Seamus McFly | Single Action Army | - |
| Sean Sullivan | Buford Tannen's Gang member | Single Action Army | - |
| Thomas F. Wilson | Buford "Mad Dog" Tannen | Single Action Army | - |
| Thomas F. Wilson | Buford "Mad Dog" Tannen | Iver Johnson Eclipse Derringer | - |