| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Daniel Newman | Jimmy Keppler | SIG-Sauer P232 | "Ink" (S4E02) |
| Ernie Hudson | Captain Lubbock | SIG-Sauer P226 | - |
| Rick Worthy | Mike | Beretta 92FS | "Ink" (S4E02). |
| Zachary Quinto | Sylar | SIG-Sauer P226 | - |
| Zachary Quinto | Sylar | Two-tone SIG Sauer P226 | - |