| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Dougray Scott | Interpol agent Mike Whittier | Heckler & Koch P2000 | laser sight |
| Henry Ian Cusick | Udre Belicoff | Makarov PM | - |
| Henry Ian Cusick | Udre Belicoff | RPD | dual-wielded |
| Henry Ian Cusick | Udre Belicoff | Arsenal Shipka | - |
| Henry Ian Cusick | Udre Belicoff | M4A1 | - |
| Henry Ian Cusick | Udre Belicoff | Standalone M203 Grenade Launcher | - |
| Michael Offei | Interpol Special Agent Jenkins | Heckler & Koch USP | Custom Sport fitted with tactical light |
| Nicky Naudé | Hitman #3 | Taurus PT92 | - |
| Timothy Olyphant | Agent 47 | Para-Ordnance P-18 | - |
| Timothy Olyphant | Agent 47 | Blaser 93 sniper rifle | bipod, custom muzzle brake |
| Timothy Olyphant | Agent 47 | Walther WA 2000 | - |
| Timothy Olyphant | Agent 47 | Heckler & Koch MP5A3 | tri-rails |
| Timothy Olyphant | Agent 47 | Arsenal SAR-M14 | - |
| Timothy Olyphant | Agent 47 | Para-Ordnance LDA | - |