| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Aaron Taylor-Johnson | Ives | Glock 17 | - |
| Anthony Molinari | Rohan | Glock 17 | - |
| Anthony Molinari | Rohan | RGD-5 hand grenade | - |
| Clémence Poésy | Laura | Beretta 92FS | - |
| Elizabeth Debicki | Kat | SIG-Sauer P230 | Suppressed |
| Elizabeth Debicki | Kat | Glock 26 | - |
| Fiona Dourif | Wheeler | Heckler & Koch HK416D | - |
| John David Washington | The Protagonist | Glock 19 | threaded barrel, suppressor |
| John David Washington | The Protagonist | Beretta 92FS | - |
| John David Washington | The Protagonist | Heckler & Koch HK416D | - |
| Kenneth Branagh | Andrei Sator | SIG-Sauer P226 | - |
| Kenneth Branagh | Andrei Sator | Beretta M12 | - |
| Robert Pattinson | Neil | M4A1 | - |
| Robert Pattinson | Neil | Glock 19 | - |
| Yuri Kolokolnikov | Volkov | Glock 19 | - |
| Yuri Kolokolnikov | Volkov | SIG-Sauer P320 | - |
| Yuri Kolokolnikov | Volkov | M4A1 Carbine | - |