| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Erwin Leder | Singe | Walther P99 | - |
| Kate Beckinsale | Selene | Walther P99 | dual-wielded; two tone, Walther LAM's, & lightened triggers |
| Kate Beckinsale | Selene | Beretta 92FS | dual-wielded; converted to full auto, added compensators |
| Kate Beckinsale | Selene | Heckler & Koch USP | - |
| Kate Beckinsale | Selene | Heckler & Koch USP Compact | - |
| Kevin Grevioux | Raze | Steyr TMP | dual-wielded |
| Michael Sheen | Lucian | Desert Eagle Mark VII | - |
| Michael Sheen | Lucian | Franchi SPAS-12 | Short barrel |
| Robbie Gee | Kahn | Heckler & Koch USP | - |
| Robbie Gee | Kahn | M4/M4A1 Carbine | - |
| Robbie Gee | Kahn | MP5A3 | - |
| Scott McElroy | Soren | Heckler & Koch MP5K | - |
| Scott Speedman | Michael Corvin | Heckler & Koch USP Compact | - |
| Shane Brolly | Kraven | Heckler & Koch USP Match | - |
| Todd Schneider | Trix | Desert Eagle Mark VII | - |