| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Adrien Brody | Royce | AA-12 | heavily customized |
| Adrien Brody | Royce | M1911A1 | customized |
| Adrien Brody | Royce | Flare Gun | - |
| Alice Braga | Isabelle | Blaser R93 Sniper Rifle | Elcan DigitalHunter scope |
| Alice Braga | Isabelle | Heckler & Koch HK45 | compensator |
| Louis Ozawa Changchien | Hanzo | Beretta 92FS Inox | - |
| Mahershala Ali | Mombasa | AKMS | - |
| Mahershala Ali | Mombasa | M1911A1 | - |
| Oleg Taktarov | Nikolai | GE M134 Minigun | hand-held |
| Oleg Taktarov | Nikolai | Tokarev TT-33 | - |
| Oleg Taktarov | Nikolai | M18A1 Claymore | - |