| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Kate Beckinsale | Selene | Beretta 92FS | Compensator; full auto conversion |
| Kate Beckinsale | Selene | Beretta 92FS Inox | Visually Modified |
| Kate Beckinsale | Selene | Walther P99 | stock footage, two tone fitted with laser |
| Kate Beckinsale | Selene | STI GP6 | Heavily modified |
| Michael Ealy | Detective Sebastian | Sage Control Ordnance Deuce Revolution | With EOtech and vertical grip |
| Michael Ealy | Detective Sebastian | Taurus Judge | - |