| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Tom Cruise | IMF Agent Ethan Hunt | Beretta Cougar | - |
| Dale Dye | Barnes | Steyr TMP | - |
| Emmanuelle Béart | Claire Phelps | SIG-Sauer P228 | - |
| Henry Czerny | Eugene Kittridge | SIG-Sauer P228 | - |
| Jon Voight | Jim Phelps | CZ 82 | Suppressed |
| Jon Voight | Jim Phelps | Makarov PM | Suppressed |
| Jon Voight | Jim Phelps | Custom 2-shot pistol | Assembled from radio |