| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Matt Gerald | Cpl. Lyle Wainfleet | GAU-90 30mm Autocannon | fictional |
| Michelle Rodriguez | Trudy Chacon | Bullpup Shotgun | - |
| Michelle Rodriguez | Trudy Chacon | RDA Handgun | - |
| Sam Worthington | Jake Sully | RDA Handgun | - |
| Stephen Lang | Col. Miles Quaritch | (Avatar) - GS-221 Base Carbine Unit | - |
| Stephen Lang | Col. Miles Quaritch | (Avatar) - "WASP Gun" | - |