| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Al Pacino | Officer Frank Serpico | Colt Official Police | - |
| Al Pacino | Officer Frank Serpico | Smith & Wesson Model 36 | - |
| Al Pacino | Officer Frank Serpico | Browning Hi-Power | - |
| Al Pacino | Officer Frank Serpico | Smith & Wesson Escort | - |
| Edward Grover | Inspector Lombardo | Smith & Wesson Model 10 | - |
| F. Murray Abraham | Detective Heineman | Smith & Wesson Model 36 | uncredited |