| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Al Pacino | Alphonse "Big Boy" Caprice | M1911 | - |
| Charles Durning | Chief Brandon | Smith & Wesson Model 10 | - |
| Colm Meaney | Cop | Colt 1921A Thompson | - |
| Dick Van Dyke | Fletcher | Colt Official Police | - |
| Ed O'Ross | Itchy Oliver | M1921 Thompson | . |
| Ed O'Ross | Itchy Oliver | M1911 | . |
| Henry Silva | Influence | M1921 Thompson | With 50-drum magazine and |
| R.G. Armstrong | Pruneface | Colt 1921A Thompson | With 50-round drum magazine |
| R.G. Armstrong | Pruneface | Colt M1911 | - |
| Seymour Cassel | Sam Catchem | M1921 Thompson | - |
| Warren Beatty | Dick Tracy | Colt Model 1903/1908 | - |
| Warren Beatty | Dick Tracy | Colt 1921 Thompson | - |
| William Forsythe | Flattop Jones | Colt 1921A Thompson | - |
| William Forsythe | Flattop Jones | M1911 | - |