| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Jude Law | Dr. John Watson | Webley Bulldog | - |
| Robert Downey Jr. | Sherlock Holmes | Webley Bulldog | - |
| Robert Downey Jr. | Sherlock Holmes | Nagant M1895 Revolver | with home-made suppressor |
| Rachel McAdams | Irene Adler | Belgian Bulldog Pocket Revolver | - |