| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Tom Cruise | Major William Cage | FN SCAR-H | - |
| Tom Cruise | Major William Cage | Benelli Supernova | - |
| Tom Cruise | Major William Cage | M1911A1 | - |
| Bill Paxton | Master Sergeant Farell | SIG-Sauer P226R | - |
| Emily Blunt | Rita | SIG-Sauer P226R | - |
| Emily Blunt | Rita | FN SCAR-H | visually modified |