| # | Character | Media | Appearances |
|---|---|---|---|
| 1 | Himself | 18 | 142 |
| 2 | Sherlock Holmes | 50 | 117 |
| 3 | James Bond | 29 | 98 |
| 4 | Richard "Rick" Grimes | 12 | 97 |
| 5 | Daryl Dixon | 14 | 94 |
| 6 | Carol Peletier | 13 | 69 |
| 7 | Joe | 38 | 68 |
| 8 | Michael Westen | 7 | 65 |
| 9 | John Reese | 4 | 62 |
| 10 | Charlie | 34 | 60 |
Showing 50 of 35779 characters
| Name | Media | Appearances |
|---|---|---|
| Swan Rottmayer | 1 | 3 |
| Swatow Hung | 1 | 4 |
| Swedish mercenary Schmidt | 1 | 1 |
| Swedish soldier | 1 | 2 |
| Sweet Eddy | 1 | 3 |
| Sweet Pea | 1 | 5 |
| Sweetwater's Sheriff/Auctioneer | 1 | 1 |
| Sweety | 1 | 1 |
| Switch | 1 | 1 |
| Switek | 1 | 1 |
| Sy Preston | 1 | 1 |
| Sybil Rigg | 1 | 1 |
| Syd | 2 | 4 |
| Sydney | 1 | 1 |
| Sydney Bristow | 3 | 20 |
| Sydney Brown | 1 | 2 |
| Sydney Prince | 1 | 1 |
| Sydney Sterrat | 1 | 1 |
| Syed Ali | 1 | 1 |
| Sygda Kirbizhekov | 1 | 3 |
| Sykes | 1 | 1 |
| Syl | 1 | 3 |
| Sylar | 3 | 4 |
| Sylbert Rundine | 1 | 1 |
| Sylvain Dubor | 1 | 2 |
| Sylvain Marot | 1 | 2 |
| Sylvaine Orsini | 1 | 1 |
| Sylvette | 1 | 1 |
| Sylvia Arculin | 1 | 1 |
| Sylvia Madsen | 1 | 3 |
| Sylvia Thorton | 1 | 1 |
| Sylvia Vane | 1 | 1 |
| Sylvia Weis | 1 | 2 |
| Sylvie | 1 | 2 |
| Syoma | 2 | 2 |
| Syrian soldier | 1 | 1 |
| Syrtsov | 1 | 2 |
| Syrus | 1 | 1 |
| System Agent 2 | 1 | 1 |
| Szczepan Zaloda | 1 | 1 |
| Szymon Kowalski "Milimetr" | 1 | 1 |
| Sánchez | 1 | 2 |
| Sébastien Grenier | 1 | 1 |
| Ségal | 1 | 1 |
| T-1000 | 2 | 4 |
| T-5 Rossi | 1 | 4 |
| T-888 | 1 | 1 |
| T-888 "Water Delivery Guy" | 1 | 1 |
| T-888 Terminator | 1 | 1 |
| T-Bag | 2 | 3 |