| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Andy Mackenzie | Hoss Bender | Heckler & Koch G36K | - |
| Ryan Phillippe | Lt. Dixon Piper | Heckler & Koch MP5K | fitted with A2 stock and straight magazine |
| Ryan Phillippe | Lt. Dixon Piper | Glock 17 | - |
| Ryan Phillippe | Lt. Dixon Piper | Heckler & Koch MP5A3 | - |
| Timothy V. Murphy | Constantine Bach | Smith & Wesson 5900 Series pistol | - |
| Timothy V. Murphy | Constantine Bach | Taurus PT92 | - |
| Val Kilmer | Dieter Von Cunth | M1911A1 | With pearl grips |
| Val Kilmer | Dieter Von Cunth | Taurus PT92AFS | - |
| Val Kilmer | Dieter Von Cunth | Smith & Wesson 5903 | - |
| Will Forte | MacGruber | Taurus PT92AFS | - |
| Will Forte | MacGruber | Micro Uzi | dual-wielded |
| Will Forte | MacGruber | Colt M4A1 | - |
| Will Forte | MacGruber | M203 Grenade Launcher | on M4A1 |