| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Anthony Zerbe | Justin Sepheran | Heckler & Koch P9S | - |
| David McCallum | Illya Kuryakin | Heckler & Koch P7M8 | suppressed |
| Geoffrey Lewis | Janus | Valmet M71 | With 30-round magazine and wooden furniture |
| Geoffrey Lewis | Janus | Palmer Cap-Chur Short Range Projector | With wooden (or brown plastic) grips and front sight removed |
| George Lazenby | "JB" | Walther PPK | - |
| John Harkins | Alexi Kemp | Heckler & Koch P9S | - |
| John Harkins | Alexi Kemp | M1911A1 | - |
| Keenan Wynn | Piers Castillian | Heckler & Koch P9S | - |
| Robert Vaughn | Napoleon Solo | Heckler & Koch P7M8 | - |
| Robert Vaughn | Napoleon Solo | UNCLE Custom Pistol | based on H&K P7M8 |
| Robert Vaughn | Napoleon Solo | COP 357 Derringer | - |
| Tom Mason | Benjamin Kowalski | Heckler & Koch P7M8 | - |
| Tom Mason | Benjamin Kowalski | Intratec TEC-9 | - |