| Actor | Character | Firearm | Notes |
|---|---|---|---|
| Georg Stanford Brown | Police under the Safe | Smith & Wesson Model 19 | Episode 2 "guest star" |
| Irwin Keyes | Luca | MP40 | Episode 2 |
| John Ashton | Rocky | Smith & Wesson Model 36 | - |
| Leslie Nielsen | Det. Frank Drebin | Colt Detective Special | - |
| Peter Lupus | Norberg | Colt Detective Special | - |
| Robert Costanzo | Leo | Smith & Wesson Model 10 | "Rendezvous at Big Gulch (Terror in the Neighborhood)" (S1E05) |
| William Shatner | Himself | Colt Detective Special | opening credits, "Revenge and Remorse (The Guilty Alibi)" (S01E04) |